# interproscan ## Summary + **Module Name:** interproscan + **Support Level:** Secondary Support + **Software Access Level:** Open Access + **Home Page:** [http://www.ebi.ac.uk/Tools/pfa/iprscan/](http://www.ebi.ac.uk/Tools/pfa/iprscan/) ## Software Description InterProScan software combines several protein motifs/domains search tools together. It allows users to scan protein sequences at one time against several signature databases including Prosite, PRINTS, PFAM, ProDom, Smart, TIGRFAMs, SignlP, Trans memberane etc., and also gives GO annotation. ## General Linux To run this software [interactively](https://www.msi.umn.edu/remote-access) in a Linux environment run the commands: module load interproscan iprscan -cli -i -o For documentation, refer to the InterProScan homepage, or run the command iprscan -cli -help Other InterProScan programs are available in the directory /common/software/install/migrated/interproscan/VER/bin where VER is the version of InterProScan you are using. **Version 5.0 Available** Version 5.0 is now available through the interproscan/5.0 module. The new version is significantly different from previous versions. Please refer to the [developer\'s migration guide](https://code.google.com/p/interproscan/wiki/MigratingInterProScanVersions) to get started. Note that v5.0 replaces the iprscan command with interproscan.sh. **Version 5.23 Available, with Local Lookup Service** Version 5.23 is available on all Linux systems through the interproscan/5.23-62.0 module. This module is configured to run locally, without communicating with the InterProScan servers.  This can greatly speed up certain workflows. [Usage instructions can be found here.](https://github.com/ebi-pf-team/interproscan/wiki/HowToRun) Note that you can start the local lookup service with the command start_lookup_service.sh . This will take at least 15 minutes to start in the background, after which you can run other InterProScan commands normally. When using version 5.23, please request at least 12 processors and 8GB of memory. This version should not be run from the login nodes.