# macs ## Summary + **Module Name:** macs + **Support Level:** Primary Support + **Software Access Level:** Open Access + **Home Page:** [http://liulab.dfci.harvard.edu/MACS/index.html](http://liulab.dfci.harvard.edu/MACS/index.html) ## Software Description MACS empirically models the length of the sequenced ChIP fragments, which tends to be shorter than sonication or library construction size estimates, and uses it to improve the spatial resolution of predicted binding sites. MACS also uses a dynamic Poisson distribution to effectively capture local biases in the genome sequence, allowing for more sensitive and robust prediction. MACS compares favorably to existing ChIP-Seq peak-finding algorithms, is publicly available open source, and can be used for ChIP-Seq with or without control samples. ## General Linux To load this module for use in a Linux environment, you can run the command: module load macs Depending on where you are working, there may be more than one version of macs available. To see which modules are available for loading you can run: module avail macs